Items where Author is "Başağa, Hüveyda"

Article

Kutuk, Meryem Ozlem and Tufan, Ali Evren and Topal, Zehra and Acikbas, Ufuk and Guler, Gulen and Karakaş, Bahriye and Başağa, Hüveyda and Kilicaslan, Fethiye and Altintas, Ebru and Aka, Yeliz and Kutuk, Ozgur (2022) CYP450 2D6 and 2C19 genotypes in ADHD: not related with treatment resistance but with over-representation of 2C19 ultra-metabolizers. Drug Metabolism and Personalized Therapy, 37 (3). pp. 261-269. ISSN 2363-8907 (Print) 2363-8915 (Online)

Karakaş, Bahriye and Aka, Yeliz and Giray, Aslı and Temel, Sehime Gulsun and Acikbas, Ufuk and Başağa, Hüveyda and Gul, Ozgur and Kutuk, Ozgur (2021) Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells. Cell Death Discovery, 7 (1). ISSN 2058-7716

Aka, Yeliz and Karakaş, Bahriye and Acikbas, Ufuk and Başağa, Hüveyda and Gül, Özgür and Kütük, Özgür (2021) Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target. International Journal of Biochemistry and Cell Biology, 137 . ISSN 1357-2725 (Print) 1878-5875 (Online)

Temel, Sehime Gulsun and Giray, Aslı and Karakaş, Bahriye and Gul, Ozgur and Kozanoglu, Ilknur and Celik, Husnu and Başağa, Hüveyda and Acikbas, Ufuk and Sucularli, Ceren and Oztop, Sidika and Aka, Yeliz and Kutuk, Ozgur (2020) RAB25 confers resistance to chemotherapy by altering mitochondrial apoptosis signaling in ovarian cancer cells. Apoptosis, 25 (11-12). pp. 799-816. ISSN 1360-8185 (Print) 1573-675X (Online)

Birinci, Yelda and Kolkar, Javed and Çetin, Öznur and Başağa, Hüveyda (2020) Quercetin in the form of a nano-antioxidant (QTiO(2)) provides stabilization of quercetin and maximizes its antioxidant capacity in the mouse fibroblast model. Enzyme and Microbial Technology, 138 . ISSN 0141-0229 (Print) 1879-0909 (Online)

Buleandra, Mihaela and Moldovan, Zenovia and Badea, Irinel Adriana and David, Iulia Gabriela and Popa, Dana Elena and Oprea, Eliza and Tekiner Çağlar, Tugce Ayca and Başağa, Hüveyda (2020) Comparative assessment of the volatile profile, antioxidant capacity and cytotoxic potential of different preparation of Millefolli herba samples. Revista de Chimie, 71 (3). pp. 69-78. ISSN 0034-7752

Sakul, Arzu and Ozansoy, Mehmet and Elibol, Birsen and Ayla, Şule and Günal, Mehmet Yalçın and Yozgat, Yasemin and Başağa, Hüveyda and Şahin, Kazım and Kazancıoğlu, Rümeysa and Kılıç, Ulkan (2019) Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice. Turkish Journal of Biology, 43 (3). pp. 179-188. ISSN 1300-0152 (Print) 1303-6092 (Online)

Timuçin, Ahmet Can and Başağa, Hüveyda and Kütük, Özgür (2019) Selective targeting of antiapoptotic BCL-2 proteins in cancer. Medicinal Research Reviews, 39 (1). pp. 146-175. ISSN 0198-6325 (Print) 1098-1128 (Online)

Manda, Gina and Hinescu, Mihail E. and Neagoe, Ionela V. and Ferreira, Luis F. V. and Boscencu, Rica and Vasos, Paul and Başağa, Hüveyda and Cuadrado, Antonio (2018) Emerging therapeutic targets in oncologic photodynamic therapy. Current Pharmaceutical Design, 24 (44). pp. 5268-5295. ISSN 1381-6128 (Print) 1873-4286 (Online)

Karakaş, Bahriye and Özmay, Yeliz and Başağa, Hüveyda and Gül, Özgür and Kütük, Özgür (2018) Distinct apoptotic blocks mediate resistance to panHER inhibitors in HER2+breast cancer cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1865 (8). pp. 1073-1087. ISSN 0167-4889 (Print) 0006-3002 (Online)

Vuruşaner Aktaş, Beyza and Gargiulo, Simona and Testa, Gabriella and Gamba, Paola and Leonarduzzi, Gabriella and Poli, Giuseppe and Başağa, Hüveyda (2018) The role of autophagy in survival response induced by 27-hydroxycholesterol in human promonocytic cells. Redox Biology, 17 . pp. 400-410. ISSN 2213-2317

Timuçin, Ahmet Can and Başağa, Hüveyda (2017) Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-kappa B pathway and anti-apoptotic Bcl-2. Free Radical Biology and Medicine (SI), 111 . pp. 209-218. ISSN 0891-5849 (Print) 1873-4596 (Online)

Kütük, Özgür and Aytan, Nurgül and Karakaş, Bahriye and Kurt, Aslı Giray and Açıkbaş, Ufuk and Temel, Sehime Gülsun and Başağa, Hüveyda (2017) Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells. PLoS One, 12 (8). ISSN 1932-6203

Bodur, Çağrı and Karakaş, Bahriye and Timuçin, Ahmet Can and Tezil, Tuğsan and Başağa, Hüveyda (2016) AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins. Molecular Carcinogenesis, 55 (11). pp. 1584-1597. ISSN 1098-2744 (Print) 1098-2744 (Online)

Timuçin, Ahmet Can and Başağa, Hüveyda (2016) SIRT6 is a positive regulator of aldose reductase expression in U937 and HeLa cells under osmotic stress: in vitro and in silico insights. PLoS One, 11 (8). ISSN 1932-6203

Vuruşaner Aktaş, Beyza and Leonarduzzi, Gabriella and Gamba, Paola and Poli, Giuseppe and Başağa, Hüveyda (2016) Oxysterols and mechanisms of survival signaling. Molecular Aspects of Medicine, 49 . pp. 8-22. ISSN 0098-2997 (Print) 1872-9452 (Online)

David, Iulia Gabriela and Buleandra, Mihaela and Popa, Dana Elena and Bizgan, Ana-Maria Cristina and Moldovan, Zenovia and Badea, Irinel-Adriana and Iorgulescu, Emilia Elena and Tekiner, Tuğçe Ayça and Başağa, Hüveyda (2016) Voltammetric determination of polyphenolic content as rosmarinic acid equivalent in tea samples using pencil graphite electrodes. Journal of Food Science and Technology, 53 (6). pp. 2589-2596. ISSN 0022-1155 (Print) 0975-8402 (Online)

Vuruşaner Aktaş, Beyza and Başağa, Hüveyda (2016) Nrf2 antioxidant defense is involved insurvival signaling elicited by 27 hydroxycholesterol in human promonocytic cells. (Accepted)

Vuruşaner, Beyza and Gamba, Paola and Gargiulo, Simona and Testa, Gabriella and Staurenghi, Erica and Leonarduzzi, Gabriella and Poli, Giuseppe and Başağa, Hüveyda (2016) Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells. Free Radical Biology and Medicine, 91 . pp. 93-104. ISSN 0891-5849 (Print) 1873-4596 (Online)

Pajares, Marta and Jiménez-Moreno, Natalia and Dias, Irundika H.K. and Debelec, Bilge and Vucetic, Milica and Fladmark, Kari E. and Başağa, Hüveyda and Ribaric, Samo and Milisav, Irina and Cuadrado, Antonio (2015) Redox control of protein degradation. Redox Biology, 6 . pp. 409-420. ISSN 2213-2317 (Print) 2213-2317 (Online)

Timuçin, Ahmet Can and Bodur, Çağrı and Başağa, Hüveyda (2015) SIRT1 contributes to aldose reductase expression through modulating NFAT5 under osmotic stress: in vitro and in silico insights. Cellular Signalling, 27 (11). pp. 2160-2172. ISSN 0898-6568 (Print) 1873-3913 (Online)

David, Iulia Gabriela and Bizgan, Ana-Maria Cristina and Popa, Dana Elena and Buleandra, Mihaela and Moldovan, Zenovia and Badea, Irinel Adriana and Tekiner, Tuğçe Ayça and Başağa, Hüveyda and Ciucu, Anton A. (2015) Rapid determination of total polyphenolic content in tea samples based on caffeic acid voltammetric behaviour on a disposable graphite electrode. Food Chemistry, 173 . pp. 1059-1065. ISSN 0308-8146 (Print) 1873-7072 (Online)

Vuruşaner, Beyza and Gamba, Paola and Testa, Gabriella and Gargiulo, Simona and Biasi, Fiorella and Zerbinati, Chiara and Iuliano, Luigi and Leonarduzzi, Gabriella and Başağa, Hüveyda and Poli, Giuseppe (2014) Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation. Free Radical Biology and Medicine, 77 . pp. 376-385. ISSN 0891-5849 (Print) 1873-4596 (Online)

Tezil, Tuğsan and Başağa, Hüveyda (2014) Modulation of cell death in age related diseases. Current Pharmaceutical Design, 20 (18). pp. 3052-3067. ISSN 1381-6128 (Print) 1873-4286 (Online)

Tekiner, Tugce Ayca and Başağa, Hüveyda (2013) Role of microRNA deregulation in breast cancer cell chemoresistance and stemness. Current Medicinal Chemistry, 20 (27). pp. 3358-3369. ISSN 0929-8673 (Print) 1875-533X (Online)

Bodur, Çağrı and Kütük, Özgür and Karslı, Gizem and Isimjan, Tayirjan T. and Harrison, Paul and Başağa, Hüveyda (2013) Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling. PLoS One, 8 (2). ISSN 1932-6203

Bodur, Çağrı and Kütük, Özgür and Tezil, Tuğsan and Başağa, Hüveyda (2012) Inactivation of Bcl-2 through I kappa B kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE). Journal of Cellular Physiology, 227 (11). pp. 3556-3565. ISSN 0021-9541

Tezil, Tuğsan and Bodur, Çağrı and Kütük, Özgür and Başağa, Hüveyda (2012) IKK-beta mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death. Cellular Signalling, 24 (6). pp. 1361-1368. ISSN 0898-6568

Bodur, Çağrı and Başağa, Hüveyda (2012) Bcl-2 inhibitors: emerging drugs in cancer therapy. Current Medicinal Chemistry (CMC), 19 (12). pp. 1804-1820. ISSN 0929-8673

Vuruşaner, Beyza and Poli, Giuseppe and Başağa, Hüveyda (2012) Tumor suppressor genes and ROS: complex networks of interactions. Free Radical Biology and Medicine, 52 (1). pp. 7-18. ISSN 0891-5849 (print) ; 1873-4596 (online)

Timuçin, Can and Gül, Özgür and Kütük, Özgür and Başağa, Hüveyda (2012) Antibody array-based immunosensor for detecting cardiovascular disease risk markers. Journal of Immunoassay and Immunochemistry, 33 (3). pp. 275-290. ISSN 1532-1819

Negre-Salvayre, Anne and Auge, Nathalie and Ayala, Victoria and Başağa, Hüveyda and Boada, Jordi and Brenke, Rainer and Chapple, Sarah and Cohen, Guy and Feher, Janos and Grune, Tilman and Lengyel, Gabriella and Mann, Giovanni E. and Pamplona, Reinald and Poli, Giuseppe and Portero-Otin, Manuel and Riahi, Yael and Salvayre, Robert and Sasson, Shlomo and Serrano, Jose and Shamni, Ofer and Siems, Werner and Siow, Richard C. M. and Wiswedel, Ingrid and Zarkovic, Kamelija and Zarkovic, Neven (2010) Pathological aspects of lipid peroxidation. Free Radical Research (Sp. Iss. SI), 44 (10). pp. 1125-1171. ISSN 1071-5762

Kütük, Özgür and Temel, Sehime Gülsun and Tolunay, Sahsine and Başağa, Hüveyda (2010) Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL. European Journal of Cancer, 46 (13). pp. 2494-2505. ISSN 0959-8049

Arısan, Elif Damla and Kütük, Özgür and Tezil, Tuğsan and Bodur, Çağrı and Telci, Dilek and Başağa, Hüveyda (2010) Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells. Breast Cancer Research and Treatment, 119 (2). pp. 271-281. ISSN 0167-6806 (Print) 1573-7217 (Online)

Telci, Dilek and Collighan, Russell John and Başağa, Hüveyda and Griffin, Martin (2009) Increased TG2 expression can result in induction of transforming growth factor beta 1, causing increased synthesis and deposition of matrix proteins, which can be regulated by nitric oxide. Journal of Biological Chemistry, 284 (43). pp. 29547-29558. ISSN 0021-9258

Kütük, Özgür and Arısan, Elif Damla and Tezil, Tuğsan and Shoshan, Maria C. and Başağa, Hüveyda (2009) Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation. Carcinogenesis, 30 (9). pp. 1517-1527. ISSN 0143-3334

Hernlund, Emma and Kütük, Özgür and Başağa, Hüveyda and Linder, Stig and Panaretakis, Theocharis and Shoshan, Maria (2009) Cisplatin-induced nitrosylation of p53 prevents its mitochondrial translocation. Free Radical Biology and Medicine, 46 (12). pp. 1607-1613. ISSN 0891-5849

Telci, Dilek and Wang, Zhuo and Li, Li and Verderio, Elisabetta A. M. and Humphries, Martin J. and Baccarini, Manuela and Başağa, Hüveyda and Griffin, Martin (2008) Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through Syndecan-4 and β1 Integrin co-signaling. The Journal of Biological Chemistry, 283 (30). pp. 20937-20947. ISSN 0021-9258

Kallempudi, Sreenivasa Saravan and Gül, Özgür and Başağa, Hüveyda and Sezerman, Uğur and Gürbüz, Yaşar (2008) Label-free biosensors for the detection and quantification of cardiovascular risk markers. Journal of Sensor Letters, 6 . pp. 1-5. ISSN 1546-198X (Print) 1546-1971 (Online)

Gül, Özgür and Calay, Ediz Süha and Sezerman, Uğur and Başağa, Hüveyda and Gürbüz, Yaşar (2007) Sandwich-type, antibody microarrays for the detection and quantification of cardiovascular risk markers. Sensors and actuators. B, Chemical, 125 (2). pp. 581-588. ISSN 0925-4005

Gül, Özgür and Calay, Ediz Süha and Başağa, Hüveyda and Gürbüz, Yaşar (2007) Sandwichtype, antibody microarrays for detection and quantification of cardiovascular risk markers. (Accepted)

Kütük, Özgür and Başağa, Hüveyda (2007) Apoptosis signalling by HNE: a role For JNK-c-Jun/AP-1 pathway. Redox Report, 12 (1-2). pp. 30-34. ISSN 13510002

Arslan, Mehmet Alper and Kütük, Özgür and Başağa, Hüveyda (2006) Protein kinases as drug targets in cancer. Current Cancer Drug Targets, 6 (7). pp. 623-634. ISSN 1568-0096

Kütük, Özgür and Başağa, Hüveyda (2006) Bcl-2 protein family: Implications in vascular apoptosis and atherosclerosis. Apoptosis, 11 (10). pp. 1661-1675. ISSN 1360-8185 (Print) 1573-675X (Online)

Başağa, Hüveyda and Kütük, Özgür (2005) Resveratrol protects against 4hne induced apoptosis by blocking jnk and c jun/ap1 signaling. (Accepted)

Kütük, Özgür and Pedrech, A. and Harris, P. and Başağa, Hüveyda (2005) Pramanicin induces apoptosis in Jurkat leukemia cells; a role for JNK, p38 and caspase activation. Apoptosis, 10 (3). pp. 597-609. ISSN 1360-8185

Arslan, Mehmet Alper and Başağa, Hüveyda and Göktuna, Serkan İsmail (2005) Signaling pathways as drug targets in cancer. Advances in Molecular Medicine, supplement, 1 (2). pp. 69-74.

Kütük, Özgür and Adli, Mazhar and Poli, Giuseppe and Başağa, Hüveyda (2004) Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts. Biofactors, 20 (1). pp. 1-10. ISSN 0951-6433

Kütük, Özgür and Başağa, Hüveyda (2004) Aspirin inhibits TNF alpha- and IL-1-induced NF-kappa B activation and sensitizes HeLa cells to apoptosis. Cytokine, 25 (5). pp. 229-237. ISSN 1043-4666

Kütük, Özgür and Başağa, Hüveyda (2003) Aspirin prevents apoptosis and NF-kappa B activation induced by H2O2 in HeLa cells. Free Radical Research, 37 (12). pp. 1267-1276. ISSN 1071-5762

Kütük, Özgür and Başağa, Hüveyda (2003) Inflammation meets oxidation: NF-kappa B as a mediator of initial lesion development in atherosclerosis. Trends in molecular medicine, 9 (12). pp. 549-557. ISSN 1471-4914

Onat, D. and Boscoboinik, D. and Azzi, A. and Başağa, Hüveyda (1999) Effect of alpha-tocopherol and silibin dihemisuccinate on the proliferation of human skin fibroblasts. Biotechnology and Applied Biochemistry, 29 (part 3). pp. 213-215. ISSN 0885-4513 (Print) 1470-8744 (Electronic)

Papers in Conference Proceedings

Vuruşaner Aktaş, Beyza and Poli, Giuseppe and Başağa, Hüveyda (2012) Survival signals induced by low concentrations of 27-hydroxycholesterol in human monocytic cells via ERK activation. In: Society for Free Radical Research International 16th Biennial Meeting, Imperial College London, UK

Bodur, Çağrı and Kütük, O. and Poli, G. and Başağa, Hüveyda (2009) Role of Bcl-2 family members in 4-hydroxynonenal (HNE) mediated apoptosis. In: Annual Meeting of the Society-for-Free-Radicals-Research-Europe, Rome, Italy

Bodur, Çağrı and Kütük, Özgür and Poli, G. and Başağa, Hüveyda (2009) Role of Bcl-2 protein family members in 4-hydroxynonenal mediated apoptosis. In: Europe Meeting 2009 of the Society-for-Free-Radicals-Research, Rome, Italy

Bodur, Çağrı and Yılmaz, Sinem and Kütük, Özgür and Başağa, Hüveyda (2007) HNE (4-hydroxynonenal ) induces apoptosis via mitochondrial pathway with the involvement of Bcl-2 family members. In: 15th Euroconference on Apoptosis, Portorož, Slovenia

Gül, Özgür and Heves, Emre and Kaynak, Mehmet and Başağa, Hüveyda and Gürbüz, Yaşar (2006) Label-free, capacitive immunosensor for protein detection. In: IEEE SENSORS 2006 Conference, Daegu, South Korea

Working Paper / Technical Report

Karaca, Esra and Telci, Dilek and Kütük, Özgür and Başağa, Hüveyda (2008) Antiapoptotic mechanism of aven in cancer cells. [Working Paper / Technical Report] Sabanci University ID:SU_FENS_2008/0001

Book

Çetindamar, Dilek and Başağa, Hüveyda (2006) Türkiye'de biyoteknoloji işbirlikleri. Rekabet Stratejileri. TÜSİAD, İstanbul.

Çetindamar, Dilek (2002) Risk sermayesi, girişimcilik ve Türkiye'nin geleceği. TÜGİAD, İstanbul.

Başağa, Hüveyda and Çetindamar, Dilek (2000) Uluslararası rekabet stratejileri: biyoteknoloji. TÜSİAD Rekabet Stratejileri Dizisi; 7. TÜSİAD, İstanbul. ISBN 975-8458-09-4

Book Section / Chapter

Kütük, Özgür and Başağa, Hüveyda (2009) Apoptotic pathways in mitochondria. In: Preedy, Victor R., (ed.) Modern Insights Into Disease From Molecules to Man. UNSPECIFIED, USA. (Accepted)