Development of molecularly imprinted polymer-based FET biosensor via oxidative chemical vapor deposition

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Can, Faruk and Akkaş Moradi, Tuğçe and Şakar, Elif Hazal and Uzun, Lokman and Özaydın İnce, Gözde (2022) Development of molecularly imprinted polymer-based FET biosensor via oxidative chemical vapor deposition. In: 16th Nanoscience and Nanotechnology Conference (NanoTR-16), Ankara, Turkey

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Abstract

Biosensors have been attracting an increasing interest in various fields including medical diagnosis and health monitoring due to its rapid, selective and sensitive detection of target analyte in real-time. As biological receptors require special environmental conditions, they limit the durability and long-term storage of the biosensors. However, molecularly imprinted polymers (MIPs) are artificially synthesized to mimic the recognition of biological macromolecules at a significantly lower cost and no need for any special storage. Here, we reported the usability of the polypyrrole (PPy) MIP as a synthetic biorecognition element on a FET based biosensor to detect CA-125 ovarian cancer biomarker. We used oxidative chemical vapor deposition (oCVD) technique which allows the conformal and controlled thin film conductive polymers, to produce MIP onto a sacrificial layer. Synthesized MIP then integrated onto the interdigitated electrode arrays to make a conductive bridge between source and drain terminals for the development of the FET biosensing platform. The oCVD technique has a great potential to be used in the development of MIP-based biosensors for the detection of target proteins without wasting as in the traditional bulk polymerization method.
Item Type: Papers in Conference Proceedings
Uncontrolled Keywords: oxidative chemical vapor deposition, molecularly imprinted polymer, FET biosensor
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Materials Science & Eng.
Faculty of Engineering and Natural Sciences > Academic programs > Mechatronics
Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Faruk Can
Date Deposited: 02 Jul 2024 15:28
Last Modified: 02 Jul 2024 15:28
URI: https://research.sabanciuniv.edu/id/eprint/49511

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