Aki, Deniz and Şenel, Esat Can and Esmaeili Rad, Monireh and Gokmenoglu, Melih Can and Onceyiz, Mesut Celil and Narayan, Roger and Gunduz, Oguzhan (2025) Hydrophilic monomer and crosslinker effects on optical and chemical properties of hydrophobic intraocular lenses (IOLs). MRS Communications . ISSN 2159-6859 (Print) 2159-6867 (Online) Published Online First https://dx.doi.org/10.1557/s43579-025-00773-2
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Official URL: https://dx.doi.org/10.1557/s43579-025-00773-2
Abstract
An experimental study was conducted to reduce glistening and minimize posterior capsule opacification (PCO) in hydrophobic intraocular lenses (IOLs). This approach involved the copolymerization of hydrophilic 2-hydroxyethyl acrylate (HEA) at various concentrations with hydrophobic monomers, along with incorporating different amounts of ethylene glycol di-methacrylate (EGDMA) as a crosslinker to optimize the chemical, thermal, and optical properties. Sixteen IOL formulations were synthesized and systematically analyzed using equilibrium water content (EWC) measurements, glass-transition temperature (Tg) measurements, and optical evaluation. Optimizing the balance of hydrophilic monomer and crosslinker effectively eliminates glistening and mitigates PCO while maintaining the essential optical property of hydrophobic IOLs.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Biomaterial; Polymer; Polymerization |
| Divisions: | Sabancı University Nanotechnology Research and Application Center |
| Depositing User: | Monireh Esmaeili Rad |
| Date Deposited: | 02 Sep 2025 14:55 |
| Last Modified: | 02 Sep 2025 14:55 |
| URI: | https://research.sabanciuniv.edu/id/eprint/52092 |
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