Aki, Deniz and Şenel, Esat Can and Esmaeili Rad, Monireh and Gokmenoglu, Melih Can and Onceyiz, Mesut Celil and Narayan, Roger and Gunduz, Oguzhan (2025) Hydrophilic monomer and crosslinker effects on optical and chemical properties of hydrophobic intraocular lenses (IOLs). MRS Communications . ISSN 2159-6859 (Print) 2159-6867 (Online) Published Online First https://dx.doi.org/10.1557/s43579-025-00773-2
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Official URL: https://dx.doi.org/10.1557/s43579-025-00773-2
Abstract
An experimental study was conducted to reduce glistening and minimize posterior capsule opacification (PCO) in hydrophobic intraocular lenses (IOLs). This approach involved the copolymerization of hydrophilic 2-hydroxyethyl acrylate (HEA) at various concentrations with hydrophobic monomers, along with incorporating different amounts of ethylene glycol di-methacrylate (EGDMA) as a crosslinker to optimize the chemical, thermal, and optical properties. Sixteen IOL formulations were synthesized and systematically analyzed using equilibrium water content (EWC) measurements, glass-transition temperature (Tg) measurements, and optical evaluation. Optimizing the balance of hydrophilic monomer and crosslinker effectively eliminates glistening and mitigates PCO while maintaining the essential optical property of hydrophobic IOLs.
| Item Type: | Article |
|---|---|
| Additional Information: | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| Uncontrolled Keywords: | Biomaterial; Polymer; Polymerization |
| Divisions: | Sabancı University Nanotechnology Research and Application Center |
| Depositing User: | Monireh Esmaeili Rad |
| Date Deposited: | 02 Sep 2025 14:55 |
| Last Modified: | 16 Dec 2025 11:48 |
| URI: | https://research.sabanciuniv.edu/id/eprint/52092 |
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