Usage of 3D-printed scaffolds manufactured with bio-based photopolymer resin via 3D DLP in tissue engineering

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Tezel, Özge and Kahraman, Memet Vezir and Ceylan, Ramazan and Açıksarı, Ayşegül and Demir, Ebru and Çetinel, Sibel (2025) Usage of 3D-printed scaffolds manufactured with bio-based photopolymer resin via 3D DLP in tissue engineering. Journal of Polymers and the Environment, 33 (7). pp. 3013-3028. ISSN 1566-2543 (Print) 1572-8919 (Online)

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Abstract

In this study, three-dimensional (3D) printed scaffolds were fabricated using a bio-based photopolymer resin derived from sustainable resources for tissue engineering applications. The resin consisted of a UV-curable bio-based fatty acid-based polyester acrylate, polyethylene glycol dimethacrylate, and a photoinitiator. To enhance porosity and biodegradability, coconut oil and poly(ethylene glycol) (PEG) were incorporated into the formulations. The curing behavior of different formulations was investigated by differential photocalorimetry (Photo-DSC), and it was observed that polyethylene glycol accelerated the curing process. The biocompatibility of the 3D printed scaffolds was evaluated using culture experiments with mouse fibroblast (L-929) cells. The obtained results demonstrate that the developed bio-based photopolymer resins have the potential to be a promising material for tissue engineering applications.
Item Type: Article
Additional Information: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/
Uncontrolled Keywords: 3D printing; 3D scaffold; Fibroblast; Photo-DSC; Photopolymerization; Tissue Engineering
Divisions: Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Sibel Çetinel
Date Deposited: 19 Aug 2025 12:15
Last Modified: 15 Jan 2026 12:17
URI: https://research.sabanciuniv.edu/id/eprint/51891

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