Evaluation of cell plating efficiency on polymer surfaces for organ-on-a-chip applications

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Zal, Gülşen and Çimen, Atike Nur and Bajwa, Rayan and Kutlu, Özlem and Yapıcı, Murat Kaya (2024) Evaluation of cell plating efficiency on polymer surfaces for organ-on-a-chip applications. In: 36th European Conference on Solid-State Transducers (EUROSENSORS XXXVI), Hungary

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Abstract

Due to their many benefits, polymers have gained popularity recently, particularly in the biomedical industry. SU-8 and polydimethylsiloxane (PDMS) in particular have drawn notice for their advanta-geous qualities, such as chemical stability and biocompatibility. Proper cellular function in biological environments depends on effective cell-surface interactions. A new method of surface modification that involves coating Poly-L-lysine (PLL) and applying oxygen plasma treatment appears to be promis-ing in improving the adhesion of HEK 293 cells to PDMS and SU-8 surfaces.
Item Type: Papers in Conference Proceedings
Uncontrolled Keywords: Cell attachment, HEK 293 cells, Hydrophilic surfaces, PDMS, Poly-L lysine
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK7800-8360 Electronics
Divisions: Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Murat Kaya Yapıcı
Date Deposited: 07 Mar 2025 14:42
Last Modified: 07 Mar 2025 14:42
URI: https://research.sabanciuniv.edu/id/eprint/51113

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