Advances and challenges toward neural regenerative medicine

Official URL: https://dx.doi.org/10.1016/B978-0-12-820223-4.00001-2

Neurodegenerative diseases such as Alzheimer, Parkinson, and Huntington diseases are injuries which have a serious negative effect on the structure and the function of the central nervous system, cognitive behavior, memory, and ability to move in patients. It is estimated that the number of people who are affected by these diseases will be increased in future decades. Unfortunately, there is no effective clinical treatment for many of the neurodegenerative disorders. Accordingly, with the advent of nanotechnology, many efforts have been made to solve the problems like crossing the blood–brain barrier and reaching the target site in the brain using novel techniques and material in field of design, synthesis, and surface modification of nanomedicine. Different types of nanomedicine have been used and studied including polymeric nanoparticles, as well as liposomes, and functionalized nanosystems. In the present chapter, we explain the challenges and advances of nanomedicine for treatment of neurodegenerative diseases after a brief description about each neurodegenerative disorders and barriers which are in front of efficient and long-term therapies.