Non-spherical nanostructures in nanomedicine: from noble metal nanorods to transition metal dichalcogenide nanosheets

Makvandi, Pooyan and Zarepour, Atefeh and Zheng, Xuanqi and Agarwal, Tarun and Ghomi, Matineh and Sartorius, Rossella and Zare, Ehsan Nazarzadeh and Zarrabi, Ali and Wu, Aimin and Maiti, Tapas Kumar and Smith, Bryan Ronain and Varma, Rajender S. and Tay, Franklin R. and Mattoli, Virgilio (2021) Non-spherical nanostructures in nanomedicine: from noble metal nanorods to transition metal dichalcogenide nanosheets. Applied Materials Today, 24 . ISSN 2352-9407

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Abstract

Non-spherical metal nanomaterials such as noble metal or transition metal dichalcogenides and MXenes have been employed in different biomedical facets. Because the biological properties of these nanocompounds are governed by their architecture and composition, such factors should be considered prior to their adoption for clinical use. The architecture of metal-based nanomaterials affects cell viability by virtue of the variable geometry of these nanomaterials as well as their physicochemical interactions with mammalian cell membranes. In the present review, the effects of parameters such as interfacial interaction and aspect ratio on cellular uptake of non-spherical metallic nanomaterials will be discussed. The application of these nanomaterials as biosensors, in cancer diagnosis and therapy, tissue engineering and regenerative medicine will also be thoroughly reviewed.
Item Type: Article
Uncontrolled Keywords: Anti-cancer therapy; Cancer diagnosis; Endocytosis mechanism; MXene; Tissue engineering; Transition metal dichalcogenides
Divisions: Sabancı University Nanotechnology Research and Application Center
Depositing User: Ali Zarrabi
Date Deposited: 01 Sep 2022 20:32
Last Modified: 01 Sep 2022 20:32
URI: https://research.sabanciuniv.edu/id/eprint/43529

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