Fundamentals, biomedical applications and future potential of micro-scale cavitation-a review

Seyedmirzaei Sarraf, Seyedali and Rokhsar Talabazar, Farzad and Namlı, İlayda and Maleki, Mohammadamin and Sheibani Aghdam, Araz and Gharib, Ghazeleh and Grishenkov, Dmitry and Ghorbani, Morteza and Koşar, Ali (2022) Fundamentals, biomedical applications and future potential of micro-scale cavitation-a review. Lab on a Chip, 22 (12). pp. 2237-2258. ISSN 1473-0197 (Print) 1473-0189 (Online)

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Thanks to the developments in the area of microfluidics, the cavitation-on-a-chip concept enabled researchers to control and closely monitor the cavitation phenomenon in micro-scale. In contrast to conventional scale, where cavitation bubbles are hard to be steered and manipulated, lab-on-a-chip devices provide suitable platforms to conduct smart experiments and design reliable devices to carefully harness the collapse energy of cavitation bubbles in different bio-related and industrial applications. However, bubble behavior deviates to some extent when confined to micro-scale geometries in comparison to macro-scale. Therefore, fundamentals of micro-scale cavitation deserve in-depth investigations. In this review, first we discussed the physics and fundamentals of cavitation induced by tension-based as well as energy deposition-based methods within microfluidic devices and discussed the similarities and differences in micro and macro-scale cavitation. We then covered and discussed recent developments in bio-related applications of micro-scale cavitation chips. Lastly, current challenges and future research directions towards the implementation of micro-scale cavitation phenomenon to emerging applications are presented.
Item Type: Article
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Mechatronics
Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Araz Sheibani Aghdam
Date Deposited: 29 Jun 2022 14:41
Last Modified: 23 Sep 2022 10:11

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