title   
  

Single cell level dielectrophoretic responses & dielectrophoretic deformations of monocytes to quantify population heterogeneity

Şengül, Esra and Kara, Osman and Yıldızhan, Yağmur and Martinez-Duarte, Rodrigo and Elitaş, Meltem (2020) Single cell level dielectrophoretic responses & dielectrophoretic deformations of monocytes to quantify population heterogeneity. In: 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Montreal, QC, Canada

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Abstract

Single-cell dielectrophoretic movement and dielectrophoretic deformation of monocyte cells were interrogated applying 20 V pp , 50 kHz to 1 MHz signal in the 3D carbon electrode array. Heterogeneity of the monocyte population is shown in terms of the crossover frequencies, translational movement, and deformation index of the cells. The results presented that crossover range for monocytes was 100 kHz - 200 kHz, the translational movement of the cells was rapidly altered when the initial positions of the cells were in the negative dielectrophoretic region. Finally, the deformation index of the monocyte population varied from 0.5 to 1.5.
Item Type: Papers in Conference Proceedings
Subjects: R Medicine > R Medicine (General)
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK1-4661 Electrical engineering. Electronics Nuclear engineering
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Mechatronics
Faculty of Engineering and Natural Sciences
Depositing User: Meltem Elitaş
Date Deposited: 18 Sep 2020 09:47
Last Modified: 03 Aug 2023 22:56
URI: https://research.sabanciuniv.edu/id/eprint/40254

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