Biomedical device prototype based on small scale hydrodynamic cavitation

Ghorbani, Morteza and Sözer, Canberk and Alcan, Gökhan and Ünel, Mustafa and Ekici, Sinan and Üvet, Hüseyin and Koşar, Ali (2018) Biomedical device prototype based on small scale hydrodynamic cavitation. AIP Advances, 8 (3). ISSN 2158-3226

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Abstract

This study presents a biomedical device prototype based on small scale hydrodynamic cavitation. The application of small scale hydrodynamic cavitation and its integration to a biomedical device prototype is offered as an important alternative to other techniques, such as ultrasound therapy, and thus constitutes a local, cheap, and energy-efficient solution, for urinary stone therapy and abnormal tissue ablation (e.g., benign prostate hyperplasia (BPH)). The destructive nature of bubbly, cavitating, flows was exploited, and the potential of the prototype was assessed and characterized. Bubbles generated in a small flow restrictive element (micro-orifice) based on hydrodynamic cavitation were utilized for this purpose. The small bubbly, cavitating, flow generator (micro-orifice) was fitted to a small flexible probe, which was actuated with a micromanipulator using fine control. This probe also houses an imaging device for visualization so that the emerging cavitating flow could be locally targeted to the desired spot. In this study, the feasibility of this alternative treatment method and its integration to a device prototype were successfully accomplished.
Item Type: Article
Subjects: T Technology > T Technology (General)
R Medicine > R Medicine (General)
T Technology > TJ Mechanical engineering and machinery
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Biological Sciences & Bio Eng.
Faculty of Engineering and Natural Sciences > Academic programs > Mechatronics
Faculty of Engineering and Natural Sciences
Depositing User: Ali Koşar
Date Deposited: 13 Jul 2018 14:47
Last Modified: 23 May 2023 15:45
URI: https://research.sabanciuniv.edu/id/eprint/34352

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