Kinetic study of autophagy activation in fibroblasts interacted with single tumor cell in microfluidic platform

Kim, Junyoung and Karakaş Schüller, Hacer Ezgi and Choi, Yong-Jun and Gözüaçık, Devrim and Cho, Yoon-Kyoung (2015) Kinetic study of autophagy activation in fibroblasts interacted with single tumor cell in microfluidic platform. In: Annual Autumn Meeting of The Korean BioChip Society, Gangwon, S. Korea

[thumbnail of Kore_abstract.pdf] PDF
Kore_abstract.pdf

Download (18kB)

Abstract

Communication between tumor and carcinoma associated fibroblast cells (CAFs) become hot topic in cancer research recently because of their roles in tumor proliferation, metastasis and angiogenesis. Tumor cells interact with fibroblasts and make fibroblasts transdifferentiate to CAFs and autophagy in CAFs is induced. [1] To study mechanism of autophagy of CAFs by tumors, we try to develop a high throughput screening chip based on a single tumor cell-to-fibroblasts interaction. Junyoung Kim, Hacer Ezgi Karakas, Yongjun Choi, Devrim Gozuacik, Yoon-Kyoung Cho, Proceedings of Anuual Autumn Meeting of the Korean BioChip Society'15, Gangwon, Korea, pp 126, 2015
Item Type: Papers in Conference Proceedings
Uncontrolled Keywords: Single cell, High throughput screening device, Autophagy, Tumor and Fibroblasts
Subjects: Q Science > QH Natural history > QH506 Molecular biology
T Technology > T Technology (General)
R Medicine > R Medicine (General)
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Biological Sciences & Bio Eng.
Faculty of Engineering and Natural Sciences
Depositing User: Devrim Gözüaçık
Date Deposited: 13 Nov 2016 19:58
Last Modified: 26 Apr 2022 09:23
URI: https://research.sabanciuniv.edu/id/eprint/29669

Actions (login required)

View Item
View Item