Hierarchical and spatial modeling and bio-additive manufacturing of multi-material constructs

Khani, Navid and Nadernezhad, Ali and Bartolo, Paulo and Koç, Bahattin (2017) Hierarchical and spatial modeling and bio-additive manufacturing of multi-material constructs. CIRP Annals - Manufacturing Technology, 66 (1). pp. 229-232. ISSN 0007-8506 (Print) 1726-0604 (Online)

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Official URL: http://dx.doi.org/10.1016/j.cirp.2017.04.132


In this paper, a novel method of integrated modelling and bio-additive manufacturing of hybrid bioinspired structures is presented. An algorithm is developed to generate optimized and continuous path plan while changing material and internal composition spatially and hierarchically based on the assigned functionality. Biodegradable polymers and hydrogels are used as reinforcing and biological functional bioinks respectively. A new hybrid multi-head 3D bioprinter is developed to manufacture designed three-dimensional constructs depositing bioinks layer-by-layer. Simultaneous incorporation of multiple deposition heads and integrated path planning provide the benefits of using the deposition-on-demand of multi-material bio-inks. The modelled constructs are analyzed and bioprinted.

Item Type:Article
Additional Information:WoS Document Type: Article; Proceedings Paper / Conference: 67th General Assembly of International-Academy-for-Production-Engineering (CIRP) / Location: Lugano, SWITZERLAND / Date: AUG 20-26, 2017
Uncontrolled Keywords:Biomanufacturing; 3D bioprinting; Modelling of multi-functional structures
Subjects:T Technology > TA Engineering (General). Civil engineering (General) > TA164 Bioengineering
T Technology > TA Engineering (General). Civil engineering (General) > TA401-492 Materials of engineering and construction. Mechanics of materials
ID Code:33738
Deposited By:Bahattin Koç
Deposited On:09 Sep 2017 12:59
Last Modified:22 May 2019 13:56

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