3D Bioprinting of aortic structures with HDF cells

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Koç, Bahattin and Özler, Saime Burçe and Küçükgül, Can and Altunbek, Mine and Sen, O. and Çulha, M. (2014) 3D Bioprinting of aortic structures with HDF cells. In: Termis EU 2014 Congress, Genova, Italy

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Traditionally, tissue engineering strategies for damaged or diseased large blood vessels are based on scaffolds. Following the cell-seeding and surgical implantation of scaffold, there could be immunogenic reactions and complications due to the limitations of scaffold biomaterials. Therefore, recent vascular tissue engineering studies tends to scaffold-free techniques [1, 2]. In this research, a novel biomimetic computer-aided design and three-dimensional (3D) bioprinting techniques are developed to optimize bioprinting of scaffold-free macrovascular structures biomimicking a real human aorta. Live human dermal fibroblast cells (HDF) aggregates and support structures (hydrogels) are 3D bioprinted layer-by-layer according to the developed self-supporting computer model to form biomimetic aortic vessel structures.

Item Type:Papers in Conference Proceedings
Additional Information:Document Type:Meeting Abstract
Subjects:T Technology > T Technology (General)
R Medicine > R Medicine (General)
T Technology > TP Chemical technology > TP0248.13 Biotechnology
ID Code:26342
Deposited By:Bahattin Koç
Deposited On:12 Dec 2014 14:32
Last Modified:02 Aug 2019 15:06

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