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A new nanocrystalline diamond-based biosensor for the detection of cardiovascular risk markers

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Qureshi, Anjum and Kallempudi, S. Saravan and Gürbüz, Yaşar and Howell, Mick and Kang, Weng P. and Davidson, Jimmy L. (2009) A new nanocrystalline diamond-based biosensor for the detection of cardiovascular risk markers. In: 23rd Eurosensors Conference, Lausanne, Switzerland

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Official URL: http://dx.doi.org/10.1016/j.proche.2009.07.269

Abstract

In this paper, a new method to probe associative interactions of C-reactive protein (CRP) antigen with CRP antibody immobilized on a gold-interdigitated diamond electrodes was investigated. The CRP antigen detection was performed by capacitive/dielectric-constant measurements. Our results showed that the dynamic detection range using optimized conditions for a given antibody concentration (100 μg/ml) was found to be in the range 25-800 ng/ml of CRP-antigen. Biosensor developed in this study can be potentially used for detection of elevated CRP levels in suspected subjects for early diagnosis.

Item Type:Papers in Conference Proceedings
Uncontrolled Keywords:Nanocrystalline diamond; Gold interdigitated; C-reactive protein; Biosensor
Subjects:UNSPECIFIED
ID Code:13640
Deposited By:Yaşar Gürbüz
Deposited On:30 Dec 2009 16:14
Last Modified:24 Jul 2019 14:56

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