Items where Author is "Kütük, Özgür"

Article

Aka, Yeliz and Karakaş, Bahriye and Acikbas, Ufuk and Başağa, Hüveyda and Gül, Özgür and Kütük, Özgür (2021) Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target. International Journal of Biochemistry and Cell Biology, 137 . ISSN 1357-2725 (Print) 1878-5875 (Online)

Timuçin, Ahmet Can and Başağa, Hüveyda and Kütük, Özgür (2019) Selective targeting of antiapoptotic BCL-2 proteins in cancer. Medicinal Research Reviews, 39 (1). pp. 146-175. ISSN 0198-6325 (Print) 1098-1128 (Online)

Kılıç Kurt, Zuhal and Bakar Ateş, Filiz and Karakaş, Bahriye and Kütük, Özgür (2018) Cytotoxic and apoptotic effects of novel pyrrolo[2,3-d]pyrimidine derivatives containing urea moieties on cancer cell lines. Anti-Cancer Agents in Medicinal Chemistry, 18 (9). pp. 1303-1312. ISSN 1871-5206 (Print) 1875-5992 (Online)

Karakaş, Bahriye and Özmay, Yeliz and Başağa, Hüveyda and Gül, Özgür and Kütük, Özgür (2018) Distinct apoptotic blocks mediate resistance to panHER inhibitors in HER2+breast cancer cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1865 (8). pp. 1073-1087. ISSN 0167-4889 (Print) 0006-3002 (Online)

Kütük, Özgür and Aytan, Nurgül and Karakaş, Bahriye and Kurt, Aslı Giray and Açıkbaş, Ufuk and Temel, Sehime Gülsun and Başağa, Hüveyda (2017) Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells. PLoS One, 12 (8). ISSN 1932-6203

Bodur, Çağrı and Kütük, Özgür and Karslı, Gizem and Isimjan, Tayirjan T. and Harrison, Paul and Başağa, Hüveyda (2013) Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling. PLoS One, 8 (2). ISSN 1932-6203

Bodur, Çağrı and Kütük, Özgür and Tezil, Tuğsan and Başağa, Hüveyda (2012) Inactivation of Bcl-2 through I kappa B kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE). Journal of Cellular Physiology, 227 (11). pp. 3556-3565. ISSN 0021-9541

Tezil, Tuğsan and Bodur, Çağrı and Kütük, Özgür and Başağa, Hüveyda (2012) IKK-beta mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death. Cellular Signalling, 24 (6). pp. 1361-1368. ISSN 0898-6568

Timuçin, Can and Gül, Özgür and Kütük, Özgür and Başağa, Hüveyda (2012) Antibody array-based immunosensor for detecting cardiovascular disease risk markers. Journal of Immunoassay and Immunochemistry, 33 (3). pp. 275-290. ISSN 1532-1819

Kütük, Özgür and Temel, Sehime Gülsun and Tolunay, Sahsine and Başağa, Hüveyda (2010) Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL. European Journal of Cancer, 46 (13). pp. 2494-2505. ISSN 0959-8049

Arısan, Elif Damla and Kütük, Özgür and Tezil, Tuğsan and Bodur, Çağrı and Telci, Dilek and Başağa, Hüveyda (2010) Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells. Breast Cancer Research and Treatment, 119 (2). pp. 271-281. ISSN 0167-6806 (Print) 1573-7217 (Online)

Kütük, Özgür and Arısan, Elif Damla and Tezil, Tuğsan and Shoshan, Maria C. and Başağa, Hüveyda (2009) Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation. Carcinogenesis, 30 (9). pp. 1517-1527. ISSN 0143-3334

Hernlund, Emma and Kütük, Özgür and Başağa, Hüveyda and Linder, Stig and Panaretakis, Theocharis and Shoshan, Maria (2009) Cisplatin-induced nitrosylation of p53 prevents its mitochondrial translocation. Free Radical Biology and Medicine, 46 (12). pp. 1607-1613. ISSN 0891-5849

Kütük, Özgür and Başağa, Hüveyda (2007) Apoptosis signalling by HNE: a role For JNK-c-Jun/AP-1 pathway. Redox Report, 12 (1-2). pp. 30-34. ISSN 13510002

Arslan, Mehmet Alper and Kütük, Özgür and Başağa, Hüveyda (2006) Protein kinases as drug targets in cancer. Current Cancer Drug Targets, 6 (7). pp. 623-634. ISSN 1568-0096

Kütük, Özgür and Başağa, Hüveyda (2006) Bcl-2 protein family: Implications in vascular apoptosis and atherosclerosis. Apoptosis, 11 (10). pp. 1661-1675. ISSN 1360-8185 (Print) 1573-675X (Online)

Başağa, Hüveyda and Kütük, Özgür (2005) Resveratrol protects against 4hne induced apoptosis by blocking jnk and c jun/ap1 signaling. (Accepted)

Kütük, Özgür and Pedrech, A. and Harris, P. and Başağa, Hüveyda (2005) Pramanicin induces apoptosis in Jurkat leukemia cells; a role for JNK, p38 and caspase activation. Apoptosis, 10 (3). pp. 597-609. ISSN 1360-8185

Kütük, Özgür and Adli, Mazhar and Poli, Giuseppe and Başağa, Hüveyda (2004) Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts. Biofactors, 20 (1). pp. 1-10. ISSN 0951-6433

Kütük, Özgür and Başağa, Hüveyda (2004) Aspirin inhibits TNF alpha- and IL-1-induced NF-kappa B activation and sensitizes HeLa cells to apoptosis. Cytokine, 25 (5). pp. 229-237. ISSN 1043-4666

Kütük, Özgür and Başağa, Hüveyda (2003) Aspirin prevents apoptosis and NF-kappa B activation induced by H2O2 in HeLa cells. Free Radical Research, 37 (12). pp. 1267-1276. ISSN 1071-5762

Kütük, Özgür and Başağa, Hüveyda (2003) Inflammation meets oxidation: NF-kappa B as a mediator of initial lesion development in atherosclerosis. Trends in molecular medicine, 9 (12). pp. 549-557. ISSN 1471-4914

Papers in Conference Proceedings

Bodur, Çağrı and Kütük, Özgür and Poli, G. and Başağa, Hüveyda (2009) Role of Bcl-2 protein family members in 4-hydroxynonenal mediated apoptosis. In: Europe Meeting 2009 of the Society-for-Free-Radicals-Research, Rome, Italy

Bodur, Çağrı and Yılmaz, Sinem and Kütük, Özgür and Başağa, Hüveyda (2007) HNE (4-hydroxynonenal ) induces apoptosis via mitochondrial pathway with the involvement of Bcl-2 family members. In: 15th Euroconference on Apoptosis, Portorož, Slovenia

Working Paper / Technical Report

Karaca, Esra and Telci, Dilek and Kütük, Özgür and Başağa, Hüveyda (2008) Antiapoptotic mechanism of aven in cancer cells. [Working Paper / Technical Report] Sabanci University ID:SU_FENS_2008/0001

Book Section / Chapter

Kütük, Özgür and Başağa, Hüveyda (2009) Apoptotic pathways in mitochondria. In: Preedy, Victor R., (ed.) Modern Insights Into Disease From Molecules to Man. UNSPECIFIED, USA. (Accepted)

Thesis

Kütük, Özgür (2006) Characterization of intracellular signaling cascades in 4-hydroxynonenal-induced apoptosis:. [Thesis]