Items where Author is "Toprak, Erdal"

Article

Kantarcıoğlu Mazmanoğlu, Işık and Gaszek, Ilona K. and Güçlü, Tandaç Fürkan and Yildiz, M. Sadik and Atılgan, Ali Rana and Toprak, Erdal and Atılgan, Canan (2024) Structural shifts in TolC facilitate efflux-mediated β-lactam resistance. Communications Biology, 7 (1). ISSN 2399-3642

Çetin, Ebru and Güçlü, Tandaç Fürkan and Kantarcıoğlu, Işık and Gaszek, Ilona K. and Toprak, Erdal and Atılgan, Ali Rana and Dedeoglu, Burcu and Atılgan, Canan (2023) Kinetic barrier to enzyme inhibition is manipulated by dynamical local interactions in E. coli DHFR. Journal of Chemical Information and Modeling, 63 (15). pp. 4839-4849. ISSN 1549-9596 (Print) 1549-960X (Online)

Gaszek, Ilona K. and Kantarcıoğlu, Işık and Yildiz, M. Sadik and Sari, Levent and Ahmed, Ayesha and Katz, Alan and Lin, Milo M. and Toprak, Erdal (2023) Molecular evolution of extended spectrum beta-lactam resistance. Biophysical Journal, 122 (3S1). 21a-21a. ISSN 0006-3495 (Print) 1542-0086 (Online)

Manna, Madhu Sudan and Tamer, Yusuf Talha and Gaszek, Ilona and Poulides, Nicole and Ahmed, Ayesha and Wang, Xiaoyu and Toprak, Furkan C.R. and Woodard, Da Nae R. and Koh, Andrew Y. and Williams, Noelle S. and Borek, Dominika and Atılgan, Ali Rana and Hulleman, John D. and Atılgan, Canan and Tambar, Uttam and Toprak, Erdal (2021) A trimethoprim derivative impedes antibiotic resistance evolution. Nature Communications, 12 (1). ISSN 2041-1723

Tamer, Yusuf Talha and Gazsek, Ilona K. and Abdizadeh, Haleh and Batur, Tuğçe and Reynolds, Kimberly and Atılgan, Ali Rana and Atılgan, Canan and Toprak, Erdal (2019) High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection. Molecular Biology and Evolution, 36 (7). pp. 1533-1550. ISSN 0737-4038 (Print) 1537-1719 (Online)

Abdizadeh, Haleh and Tamer, Yusuf Talha and Acar, Ömer and Toprak, Erdal and Atılgan, Ali Rana and Atılgan, Canan (2017) Increased substrate affinity in the escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance. Physical Chemistry Chemical Physics, 19 (18). pp. 11416-11428. ISSN 1463-9076 (Print) 1463-9084 (Online)

Öz, Tuğçe and Güvenek, Ayşegül and Yıldız, Sadık and Karaboğa, Enes and Tamer, Yusuf Talha and Mumcuyan, Nirva and Ozan, Vedat Burak and Şentürk, Gizem Hazal and Çokol, Murat and Yeh, Pamela and Toprak, Erdal (2014) Strength of selection pressure is an important parameter contributing to the complexity of antibiotic resistance evolution. Molecular Biology and Evolution, 31 (9). pp. 2387-2401. ISSN 0737-4038 (Print) 1537-1719 (Online)

Toprak, Erdal and Veres, Adrian and Yıldız, Muhammed Sadık and Pedraza, Juan M. and Chait, Remy and Paulsson, Johan and Kishony, Roy (2013) Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition. Nature Protocols, 8 (3). pp. 555-567. ISSN 1754-2189 (Print) 1750-2799 (Online)

Toprak, Erdal (2011) Evolutionary paths to strong antibiotic resistance under dynamically sustained drug stress. (Accepted)

Papers in Conference Proceedings

Abdizadeh, Haleh and Acar, Ömer and Güçlü, Tandaç Fürkan and Tamer, Yusuf Talha and Altınuşak, Tuğçe and Toprak, Erdal and Atılgan, Ali Rana and Atılgan, Canan (2016) Computational assessment of trimethoprim resistance in dihydrofolate reductase. In: 60th Annual Meeting of the Biophysical Society, Los Angeles, CA

Toprak, Erdal and Palmer, Adam C. and Kim, Seungsoo and Veres, Adrian and Bershtein, Shimon and Kishony, Roy (2013) Evolution of antibiotic resistance through a multi-peaked adaptive landscape. In: 57th Annual Meeting of the Biophysical-Society, Philadelphia, PA