Biofabricated nanostructures and their composites in regenerative medicine

Makvandi, Pooyan and Ghomi, Matineh and Padil, Vinod V.T. and Shalchy, Faezeh and Ashrafizadeh, Milad and Askarinejad, Sina and Pourreza, Nahid and Zarrabi, Ali and Nazarzadeh Zare, Ehsan and Kooti, Mohamad and Mokhtari, Babak and Borzacchiello, Assunta and Tay, Franklin R. (2020) Biofabricated nanostructures and their composites in regenerative medicine. ACS Applied Nano Materials, 3 (7). pp. 6210-6238. ISSN 2574-0970

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Biosynthesis of nanomaterials is gaining attention as a sustainable, environmentally friendly, and reliable method for manufacturing a extensive array of nanostructures, such as metal/metal oxides and organic and hybrid materials. Green synthesis is considered a crucial tool to reduce the harsh effects associated with conventional synthesis. Nanocomposite materials containing biosynthesized nanostructures are highly sought after in regenerative medicine. In the present Review, biosynthesis of metal/metal oxides and carbon-based nanomaterials using microorganisms (e.g., bacteria and fungi) and natural compounds (e.g., polysaccharides, proteins, fruit juices, and plant extracts) is highlighted. The toxicity of biosynthesized nanoparticles for biomedical application is also reviewed in depth. The applications of bionanocomposites prepared from these ecofriendly nanoparticles in tissue engineering are reviewed to provide readers with a background for future studies.
Item Type: Article
Uncontrolled Keywords: biogenic synthesis; bone tissue regeneration; green synthesis; infection-responsive; stimulus-responsive drug delivery; wound healing
Divisions: Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Ali Zarrabi
Date Deposited: 02 Aug 2023 15:24
Last Modified: 02 Aug 2023 15:24

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