Evaluation of acoustic-based particle separation methods

Ahmad, Mansoor and Bozkurt, Ayhan and Farhanieh, Omid (2019) Evaluation of acoustic-based particle separation methods. World Journal of Engineering, 16 (6). pp. 823-838. ISSN 1708-5284

This is the latest version of this item.

Full text not available from this repository. (Request a copy)


Purpose: This paper aims to Separation and sorting of biological cells is desirable in many applications for analyzing cell properties, such as disease diagnostics, drugs delivery, chemical processing and therapeutics. Design/methodology/approach: Acoustic energy-based bioparticle separation is a simple, viable, bio-compatible and contact-less technique using, which can separate the bioparticles based on their density and size, with-out labeling the sample particles. Findings: Conventionally available bioparticle separation techniques as fluorescence and immunomagnetic may cause a serious threat to the life of the cells due to various compatibility issues. Moreover, they also require an extra pre-processing labeling step. Contrarily, label-free separation can be considered as an alternative solution to the traditional bio-particle separation methods, due to their simpler operating principles and lower cost constraints. Acoustic based particle separation methods have captured a lot of attention among the other reported label-free particle separation techniques because of the numerous advantages it offers. Practical implications: This study tries to briefly cover the developments of different acoustic-based particle separation techniques over the years. Unlike the conventional surveys on general bioparticles separation, this study is focused particularly on the acoustic-based particle separation. The study would provide a comprehensive guide for the future researchers especially working in the field of the acoustics, in studying and designing the acoustic-based particle separation techniques. Originality/value: The study insights a brief theory of different types of acoustic waves and their interaction with the bioparticles is considered, followed by acoustic-based particle separation devices reported till the date. The integration of acoustic-based separation techniques with other methods and with each other is also discussed. Finally, all major aspects like the approach, and productivity, etc., of the adopted acoustic particle separation methods are sketched in this article.
Item Type: Article
Uncontrolled Keywords: Acoustics; Bulk acoustics waves; Particle separation; Standing surface acoustic waves; Traveling surface acoustic waves
Divisions: Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Ayhan Bozkurt
Date Deposited: 31 Jul 2023 17:10
Last Modified: 31 Jul 2023 17:10
URI: https://research.sabanciuniv.edu/id/eprint/46660

Available Versions of this Item

Actions (login required)

View Item
View Item