Biomimicry in bio-manufacturing: developments in melt electrospinning writing technology towards hybrid biomanufacturing

Afghah, Ferdows and Dikyol, Caner and Altunbek, Mine and Koç, Bahattin (2019) Biomimicry in bio-manufacturing: developments in melt electrospinning writing technology towards hybrid biomanufacturing. Applied Sciences (Switzerland), 9 (17). ISSN 2076-3417

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Melt electrospinning writing has been emerged as a promising technique in the field of tissue engineering, with the capability of fabricating controllable and highly ordered complex three-dimensional geometries from a wide range of polymers. This three-dimensional (3D) printing method can be used to fabricate scaffolds biomimicking extracellular matrix of replaced tissue with the required mechanical properties. However, controlled and homogeneous cell attachment on melt electrospun fibers is a challenge. The combination of melt electrospinning writing with other tissue engineering approaches, called hybrid biomanufacturing, has introduced new perspectives and increased its potential applications in tissue engineering. In this review, principles and key parameters, challenges, and opportunities of melt electrospinning writing, and particularly, recent approaches and materials in this field are introduced. Subsequently, hybrid biomanufacturing strategies are presented for improved biological and mechanical properties of the manufactured porous structures. An overview of the possible hybrid setups and applications, future perspective of hybrid processes, guidelines, and opportunities in different areas of tissue/organ engineering are also highlighted.
Item Type: Article
Uncontrolled Keywords: Hybrid biomanufacturing; Melt electrospinning writing; Three-dimensional scaffold; Tissue engineering
Divisions: Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Integrated Manufacturing Technologies Research and Application Center
Depositing User: Mine Altunbek
Date Deposited: 27 Jul 2023 09:42
Last Modified: 27 Jul 2023 09:42

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