Nanoplasmonic biosensors: theory, structure, design, and review of recent applications

Kurt, Hasan and Pishva, Parsa and Pehlivan, Zeki Semih and Arsoy, Elif Gül and Saleem, Qandeel and Bayazıt, Mustafa Kemal and Yüce, Meral (2021) Nanoplasmonic biosensors: theory, structure, design, and review of recent applications. Analytica Chimica Acta, 1185 . ISSN 0003-2670 (Print) 1873-4324 (Online)

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Nanoplasmonic biosensing shows an immense potential to satisfy the needs of the global health industry – low-cost, fast, and portable automated systems; highly sensitive and real-time detection; multiplexing and miniaturization. In this review, we presented the theory of nanoplasmonic biosensing for popular detection schemes – SPR, LSPR, and EOT – and underline the consideration for nanostructure design, material selection, and their effects on refractometric sensing performance. Later, we covered the bottom-up and top-down nanofabrication methods for nanoplasmonic biosensors. Subsequently, we reviewed the recent examples of nanoplasmonic biosensors over a wide range of clinically relevant analytes in the diagnosis and prognosis of a wide range of diseases and conditions such as biomarker proteins, infectious bacteria, viral agents. Finally, we discussed the challenges of nanoplasmonic biosensing toward clinical translation and proposed strategic avenues to be competitive against current clinical detection methods. Hopefully, nanoplasmonic biosensing can realize its potential through successful demonstrations of clinical translation in the upcoming years.
Item Type: Article
Uncontrolled Keywords: Extraordinary optical transmission; Localized surface plasmon resonance; Nanoplasmonic biosensors; Plasmonic nanostructures; Surface plasmon resonance
Divisions: Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Parsa Pishva
Date Deposited: 30 Aug 2022 15:41
Last Modified: 30 Aug 2022 15:41

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