Time delay during the proton tunneling in the base pairs of the DNA double helix

Çelebi Torabfam, Gizem and Özçelik, Elif and Vardar, Emre and Demir, Durmuş Ali (2021) Time delay during the proton tunneling in the base pairs of the DNA double helix. Progress in Biophysics and Molecular Biology, 167 . pp. 96-103. ISSN 0079-6107 (Print) 1873-1732 (Online)

This is the latest version of this item.

Full text not available from this repository. (Request a copy)


DNA undergoes spontaneous point mutations, which are believed to be central to the evolution of the organisms and which are thought to occur by tautomerization of the canonical Guanine-Cytosine (G-C) base pair into non-canonical G∗-C∗ base pair via the double proton tunneling. In the present work, we close a gap in the literature by computing the time delay during the proton tunneling. Our results, based on the well-known dwell time and our model of the entropic time, range from femtoseconds to picoseconds, and completely agree with the time scales of the structural changes in molecules (mutation processes not the complete replication processes). The tunneling delay times are thus nonnegligible and imply that the DNA mutations can be resolved using the attosecond laser technology, if not the femtosecond technology. Our results can be relevant also for other tunneling-enabled biological processes.
Item Type: Article
Uncontrolled Keywords: Dwell time; Entropic time; G-C base Pair; Proton tunneling
Divisions: Faculty of Engineering and Natural Sciences
Depositing User: Durmuş Ali Demir
Date Deposited: 30 Aug 2022 22:15
Last Modified: 30 Aug 2022 22:15
URI: https://research.sabanciuniv.edu/id/eprint/43663

Available Versions of this Item

Actions (login required)

View Item
View Item