Nanotechnology-based strategies to evaluate and counteract cancer metastasis and neoangiogenesis

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Şen, Özlem and Emanet, Melis and Ciofani, Gianni (2021) Nanotechnology-based strategies to evaluate and counteract cancer metastasis and neoangiogenesis. Advanced Healthcare Materials, 10 (10). ISSN 2192-2640 (Print) 2192-2659 (Online)

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Abstract

Cancer metastasis is the major cause of cancer-related morbidity and mortality. It represents one of the greatest challenges in cancer therapy, both because of the ability of metastatic cells to spread into different organs, and because of the consequent heterogeneity that characterizes primary and metastatic tumors. Nanomaterials can potentially be used as targeting or detection agents owing to unique chemical and physical features that allow tailored and tunable theranostic functions. This review highlights nanomaterial-based approaches in the detection and treatment of cancer metastasis, with a special focus on the evaluation of nanostructure effects on cell migration, invasion, and angiogenesis in the tumor microenvironment.
Item Type: Article
Uncontrolled Keywords: angiogenesis; cancer; invasion; metastasis; nanomaterials
Divisions: Sabancı University Nanotechnology Research and Application Center
Depositing User: Melis Emanet
Date Deposited: 31 Aug 2022 13:36
Last Modified: 31 Aug 2022 13:36
URI: https://research.sabanciuniv.edu/id/eprint/43615

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