A study on the acoustic response of pickering perfluoropentane droplets in different media

Loskutova, Ksenia and Nimander, Didrik and Gouwy, Isabelle and Chen, Hongjian and Ghorbani, Morteza and Svagan, Anna J. and Grishenkov, Dmitry (2021) A study on the acoustic response of pickering perfluoropentane droplets in different media. ACS Omega, 6 (8). pp. 5670-5678. ISSN 2470-1343

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Acoustic droplet vaporization (ADV) is the physical process of liquid-to-gas phase transition mediated by pressure variations in an ultrasound field. In this study, the acoustic response of novel particle-stabilized perfluoropentane droplets was studied in bulk and confined media. The oil/water interface was stabilized by cellulose nanofibers. First, their acoustic responses under idealized conditions were examined to assess their susceptibility to undergo ADV. Second, the droplets were studied in a more realistic setting and placed in a confined medium. Lastly, an imaging setup was developed and tested on the droplets. The acoustic response could be seen when the amplitude of the peak negative pressure (PNP) was above 200 kPa, suggesting that this is the vaporization pressure threshold for these droplets. Increasing the PNP resulted in a decrease in signal intensity over time, suggesting a more destructive behavior. The imaging setup was able to differentiate between the droplets and the surrounding tissue. Results obtained within this study suggest that these droplets have potential in terms of ultrasound-mediated diagnostics and therapy.
Item Type: Article
Divisions: Sabancı University Nanotechnology Research and Application Center
Depositing User: Morteza Ghorbani
Date Deposited: 03 Sep 2022 15:34
Last Modified: 03 Sep 2022 15:34
URI: https://research.sabanciuniv.edu/id/eprint/43410

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