Curcumin and cardiovascular diseases: focus on cellular targets and cascades

Pourbagher-Shahri, Ali Mohammad and Farkhondeh, Tahereh and Ashrafizadeh, Milad and Talebi, Marjan and Samargahndian, Saeed (2021) Curcumin and cardiovascular diseases: focus on cellular targets and cascades. Biomedicine and Pharmacotherapy, 136 . ISSN 0753-3322 (Print) 1950-6007 (Online)

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Cardiovascular diseases (CVDs) are one of the leading causes of the most considerable mortality globally, and it has been tried to find the molecular mechanisms and design new drugs that triggered the molecular target. Curcumin is the main ingredient of Curcuma longa (turmeric) that has been used in traditional medicine for treating several diseases for years. Numerous investigations have indicated the beneficial effect of Curcumin in modulating multiple signaling pathways involved in oxidative stress, inflammation, apoptosis, and proliferation. The cardiovascular protective effects of Curcumin against CVDs have been indicated in several studies. In the current review study, we provided novel information on Curcumin's protective effects against various CVDs and potential molecular signaling targets of Curcumin. Nonetheless, more studies should be performed to discover the exact molecular target of Curcumin against CVDs.
Item Type: Article
Uncontrolled Keywords: Cardiovascular diseases; Curcumin; Molecular signaling
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Biological Sciences & Bio Eng.
Faculty of Engineering and Natural Sciences
Sabancı University Nanotechnology Research and Application Center
Depositing User: Milad Ashrafizadeh
Date Deposited: 19 Aug 2022 10:42
Last Modified: 19 Aug 2022 10:42

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