Tissue adhesives: from research to clinical translation

Bal-Öztürk, Ayça and Cecen, Berivan and Avci-Adali, Meltem and Topkaya, Seda Nur and Alarcin, Emine and Yasayan, Gokcen and Li, Yi Chen Ethan and Bulkurcuoglu, Bünyamin and Akpek, Ali and Avci, Hüseyin and Shi, Kun and Shin, Su Ryon and Hassan, Shabir (2021) Tissue adhesives: from research to clinical translation. Nano Today, 36 . ISSN 1748-0132 (Print) 1878-044X (Online)

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Sutures, staples, clips, and skin closure strips are used as the gold standard to close wounds after an injury. In spite of being the present standard of care, the utilization of these conventional methods is precarious amid complicated and sensitive surgeries such as vascular anastomosis, ocular surgeries, nerve repair, or due to the high-risk components included. Tissue adhesives function as an interface to connect the surfaces of wound edges and prevent them from separation. They are fluid or semi-fluid mixtures that can be easily used to seal any wound of any morphology-uniform or irregular. As such, they provide alternatives to new and novel platforms for wound closure methods. In this review, we offer a background on the improvement of distinctive tissue adhesives focusing on the chemistry of some of these products that have been a commercial success from the clinical application perspective. This review is aimed to provide a guide toward the innovation of tissue bioadhesive materials and their associated biomedical applications.
Item Type: Article
Uncontrolled Keywords: Anastomosis; Bioadhesives; Injury; Sutures; Tissue repair; Wound closure
Divisions: Sabancı University Nanotechnology Research and Application Center
Depositing User: IC-Cataloging
Date Deposited: 19 Aug 2022 11:41
Last Modified: 19 Aug 2022 11:41
URI: https://research.sabanciuniv.edu/id/eprint/43266

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