Monitoring single tumor interactions with fibroblasts in autophagy activation

Warning The system is temporarily closed to updates for reporting purpose.

Kim, Junyoung and Karakaş Schüller, Hacer Ezgi and Choi, Yongjun and Gözüaçık, Devrim and Cho, Yoon-Kyoung (2016) Monitoring single tumor interactions with fibroblasts in autophagy activation. In: 8th International Conference on Microtechnologies in Medicine and Biology (MMB), Seoul, S. Korea

[thumbnail of Conference_paper-Korea.pdf] PDF

Download (720kB)


In tumor microenvironment, tumors interact with stromal cells such as immune cells, mesenchymal stem cells and fibroblasts etc. Specifically, communication with fibroblasts is related to tumor survival, proliferation and metastasis. We developed a high throughput screening platform based on a single tumor cell-to-fibroblasts interaction and monitored kinetics of GFP-LC3 positive fibroblasts by single tumor. Our research can have a potential to monitor single tumor which can activate autophagy in fibroblasts and help to study the heterogeneity of tumor and mechanism between tumor and fibroblast in autophagy.
Item Type: Papers in Conference Proceedings
Uncontrolled Keywords: Microfluidics, Single-cell level analysis, Tumor, Fibroblast, Autophagy
Subjects: T Technology > T Technology (General)
Q Science > QH Natural history > QH506 Molecular biology
R Medicine > R Medicine (General)
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Biological Sciences & Bio Eng.
Faculty of Engineering and Natural Sciences
Depositing User: Devrim Gözüaçık
Date Deposited: 13 Nov 2016 17:29
Last Modified: 26 Apr 2022 09:23

Actions (login required)

View Item
View Item