Cell sheet as a bioink for 3D bioprinting

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Bakırcı, Ezgi and Toprakhisar, Burak and Zeybek, Mehmet Can and İnce, Gözde and Koç, Bahattin (2016) Cell sheet as a bioink for 3D bioprinting. In: Towards Future Regenerative Therapies (TERMIS-EU 2016), Uppsala, Sweden

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Cell sheet technology is a growing area in tissue engineering. It enables a sheet of interconnected cells which is enriched with cell-extracellular matrix (ECM) and cell-cell interactions. Poly (N-isopropylacrylamide) (PNIPAm) coating based thermoresponsive culture dishes are used as one of the advanced cell sheet technology methods [1]. It allows the surface to demonstrate temperature responsive wettability changes in aqueous environments. Different methods can be used to fabricate PNIPAm surfaces such as initiated chemical vapor deposition (iCVD) which offers a control of the polymer thickness [2]. In this research, we showed that thermoresponsive surfaces can create cell sheet which can be used as a bioink in 3D direct cell bioprinting [3]. The aim of this work is to show that cell sheets can be used to increase mechanical strength of bioink.

Item Type:Papers in Conference Proceedings
Subjects:T Technology > TP Chemical technology > TP0248.13 Biotechnology
ID Code:30871
Deposited By:Bahattin Koç
Deposited On:07 Nov 2016 11:34
Last Modified:22 May 2019 13:45

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