An IVUS image-based approach for improvement of coronary plaque characterization

Taki, Arash and Roodaki, Alireza and Setarehdan, Seyed Kamaledin and Avansari, Sara and Ünal, Gözde and Navab, Nassir (2013) An IVUS image-based approach for improvement of coronary plaque characterization. Computers in Biology and Medicine, 43 (4). pp. 268-280. ISSN 0010-4825 (Print) 1879-0534 (Online)

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Abstract

Virtual Histology-Intravascular Ultrasound (VH-IVUS) is widely used for studying atherosclerosis plaque composition. However, one of the main limitations of the VH-IVUS relates to its dependence to the Electrocardiogram (ECG)-gated acquisition. To overcome this limitation, this paper proposes a robust image-based approach for characterization of the plaques using IVUS images. The proposed method consists of three main steps of (1) shadow detection: as an efficient preprocessing step to identify and remove acoustic shadow regions; (2) feature extraction: a combination of gray-scale based features and textural descriptors; and (3) classification: to classify each pixel into one of the three classes (calcium, necrotic core and fibro-fatty). In order to evaluate the efficiency of the proposed algorithm two in-vivo and ex-vivo data sets are considered. The kappa values of 0.639 on in-vivo and 0.628 on ex-vivo tests with VH-IVUS and the histology images labeled by the experts respectively indicate the effectiveness of the proposed algorithm.
Item Type: Article
Uncontrolled Keywords: IVUS; Plaque; Characterization; Virtual histology
Subjects: R Medicine > R Medicine (General) > R858-859.7 Computer applications to medicine. Medical informatics
Divisions: Faculty of Engineering and Natural Sciences > Academic programs > Electronics
Faculty of Engineering and Natural Sciences
Depositing User: Gözde Ünal
Date Deposited: 22 Jan 2014 11:48
Last Modified: 01 Aug 2019 14:24
URI: https://research.sabanciuniv.edu/id/eprint/22684

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