An IVUS image-based approach for improvement of coronary plaque characterization

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Taki, Arash and Roodaki, Alireza and Setarehdan, Seyed Kamaledin and Avansari, Sara and Ünal, Gözde and Navab, Nassir (2013) An IVUS image-based approach for improvement of coronary plaque characterization. Computers in Biology and Medicine, 43 (4). pp. 268-280. ISSN 0010-4825 (Print) 1879-0534 (Online)

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Official URL: http://dx.doi.org/10.1016/j.compbiomed.2012.12.008


Virtual Histology-Intravascular Ultrasound (VH-IVUS) is widely used for studying atherosclerosis plaque composition. However, one of the main limitations of the VH-IVUS relates to its dependence to the Electrocardiogram (ECG)-gated acquisition. To overcome this limitation, this paper proposes a robust image-based approach for characterization of the plaques using IVUS images. The proposed method consists of three main steps of (1) shadow detection: as an efficient preprocessing step to identify and remove acoustic shadow regions; (2) feature extraction: a combination of gray-scale based features and textural descriptors; and (3) classification: to classify each pixel into one of the three classes (calcium, necrotic core and fibro-fatty). In order to evaluate the efficiency of the proposed algorithm two in-vivo and ex-vivo data sets are considered. The kappa values of 0.639 on in-vivo and 0.628 on ex-vivo tests with VH-IVUS and the histology images labeled by the experts respectively indicate the effectiveness of the proposed algorithm.

Item Type:Article
Uncontrolled Keywords:IVUS; Plaque; Characterization; Virtual histology
Subjects:R Medicine > R Medicine (General) > R858-859.7 Computer applications to medicine. Medical informatics
ID Code:22684
Deposited By:Gözde Ünal
Deposited On:22 Jan 2014 11:48
Last Modified:01 Aug 2019 14:24

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