title   
  

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, Daniel J. and Gözüaçık, Devrim and Budak, Hikmet and Autophagy, Consortium (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12 (1). pp. 1-222. ISSN 1554-8627 (Print) 1554-8635 (Online)

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Official URL: http://dx.doi.org/10.1080/15548627.2015.1100356

Abstract

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes.

Item Type:Article
Uncontrolled Keywords:autolysosome; autophagosome; chaperone-mediated autophagy; flux; LC3; lysosome; macroautophagy; phagophore; stress; vacuole
Subjects:Q Science > Q Science (General)
R Medicine > R Medicine (General)
ID Code:29641
Deposited By:Devrim Gözüaçık
Deposited On:03 Nov 2016 11:11
Last Modified:03 Nov 2016 11:11

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