Creator/Author/Editor: Başağa, Hüveyda

2012

Tekiner, Tugce Ayca and Başağa, Hüveyda (2012) Role of microRNA deregulation and cancer stem cells in drug resistant breast tumors. (Submitted)

Tezil, Tuğsan and Başağa, Hüveyda (2012) Modulation of cell death in age-related diseases. (Submitted)

Bodur, Çağrı and Kütük, Özgür and Tezil, Tuğsan and Başağa, Hüveyda (2012) Inactivation of Bcl-2 through I kappa B kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE). Journal of Cellular Physiology, 227 (11). pp. 3556-3565. ISSN 0021-9541

Bodur, Çağrı and Kütük, Özgür and Başağa, Hüveyda and Karslı, Gizem (2012) Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling. (Submitted)

Tezil, Tuğsan and Bodur, Çağrı and Kütük, Özgür and Başağa, Hüveyda (2012) IKK-beta mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death. Cellular Signalling, 24 (6). pp. 1361-1368. ISSN 0898-6568

Bodur, Çağrı and Başağa, Hüveyda (2012) Bcl-2 inhibitors: emerging drugs in cancer therapy. Current Medicinal Chemistry (CMC), 19 (12). pp. 1804-1820. ISSN 0929-8673

Vuruşaner, Beyza and Poli, Giuseppe and Başağa, Hüveyda (2012) Tumor suppressor genes and ROS: complex networks of interactions. Free Radical Biology and Medicine, 52 (1). pp. 7-18. ISSN 0891-5849 (print) ; 1873-4596 (online)

Timuçin, Can and Gül, Özgür and Kütük, Özgür and Başağa, Hüveyda (2012) Antibody array-based immunosensor for detecting cardiovascular disease risk markers. Journal of Immunoassay and Immunochemistry, 33 (3). pp. 275-290. ISSN 1532-1819

2010

Negre-Salvayre, Anne and Auge, Nathalie and Ayala, Victoria and Başağa, Hüveyda and Boada, Jordi and Brenke, Rainer and Chapple, Sarah and Cohen, Guy and Feher, Janos and Grune, Tilman and Lengyel, Gabriella and Mann, Giovanni E. and Pamplona, Reinald and Poli, Giuseppe and Portero-Otin, Manuel and Riahi, Yael and Salvayre, Robert and Sasson, Shlomo and Serrano, Jose and Shamni, Ofer and Siems, Werner and Siow, Richard C. M. and Wiswedel, Ingrid and Zarkovic, Kamelija and Zarkovic, Neven (2010) Pathological aspects of lipid peroxidation. Free Radical Research (Sp. Iss. SI), 44 (10). pp. 1125-1171. ISSN 1071-5762

Kütük, Özgür and Temel, Sehime Gülsun and Tolunay, Sahsine and Başağa, Hüveyda (2010) Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL. European Journal of Cancer, 46 (13). pp. 2494-2505. ISSN 0959-8049

Arısan, Elif Damla and Kütük, Özgür and Tezil, Tuğsan and Bodur, Çağrı and Telci, Dilek and Başağa, Hüveyda (2010) Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells. Breast Cancer Research and Treatment, 119 (2). pp. 271-281. ISSN 0167-6806 (Print) 1573-7217 (Online)

2009

Telci, Dilek and Collighan, Russell John and Başağa, Hüveyda and Griffin, Martin (2009) Increased TG2 expression can result in induction of transforming growth factor beta 1, causing increased synthesis and deposition of matrix proteins, which can be regulated by nitric oxide. Journal of Biological Chemistry , 284 (43). pp. 29547-29558. ISSN 0021-9258

Kütük, Özgür and Arısan, Elif Damla and Tezil, Tuğsan and Shoshan, Maria C. and Başağa, Hüveyda (2009) Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation. Carcinogenesis, 30 (9). pp. 1517-1527. ISSN 0143-3334

Hernlund, Emma and Kütük, Özgür and Başağa, Hüveyda and Linder, Stig and Panaretakis, Theocharis and Shoshan, Maria (2009) Cisplatin-induced nitrosylation of p53 prevents its mitochondrial translocation. Free Radical Biology and Medicine, 46 (12). pp. 1607-1613. ISSN 0891-5849

Kütük, Özgür and Başağa, Hüveyda (2009) Apoptotic pathways in mitochondria. In: Preedy , Victor R., (ed.) Modern Insights Into Disease From Molecules to Man. UNSPECIFIED, USA. (Accepted/In Press)

Bodur, Çağrı and Kütük, O. and Poli, G. and Başağa, Hüveyda (2009) Role of Bcl-2 family members in 4-hydroxynonenal (HNE) mediated apoptosis. In: Annual Meeting of the Society-for-Free-Radicals-Research-Europe, Rome, Italy

Bodur, Çağrı and Kütük, Özgür and Poli, G. and Başağa, Hüveyda (2009) Role of Bcl-2 protein family members in 4-hydroxynonenal mediated apoptosis. In: Europe Meeting 2009 of the Society-for-Free-Radicals-Research, Rome, Italy

2008

Kütük, Özgür and Arısan, Elif Damla and Tezil, Tuğsan and Başağa, Hüveyda and Shoshan, Maria C. (2008) Cisplatin overcomes Bcl-2-mediated resistance to apoptosis by activating a p53-dependent proapoptotic pathway. (Submitted)

Telci, Dilek and Wang, Zhuo and Li, Li and Verderio, Elisabetta A. M. and Humphries, Martin J. and Baccarini, Manuela and Başağa, Hüveyda and Griffin, Martin (2008) Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through Syndecan-4 and β1 Integrin co-signaling. The Journal of Biological Chemistry, 283 (30). pp. 20937-20947. ISSN 0021-9258

Karaca, Esra and Telci, Dilek and Kütük, Özgür and Başağa, Hüveyda (2008) Antiapoptotic mechanism of aven in cancer cells. [Working Paper / Technical Report] Sabanci University ID:SU_FENS_2008/0001

Kallempudi, Sreenivasa Saravan and Gül, Özgür and Başağa, Hüveyda and Sezerman, Uğur and Gürbüz, Yaşar (2008) Label-free biosensors for the detection and quantification of cardiovascular risk markers. Journal of Sensor Letters, 6 . pp. 1-5.

Arısan, Elif Damla and Tezil, Tuğsan and Kütük, Özgür and Başağa, Hüveyda (2008) Mechanism of taxane induced apoptosis in breast cancer cells. [Working Paper / Technical Report] Sabanci University ID:SU_FENS_2008/0002

2007

Gül, Özgür and Başağa, Hüveyda and Kütük, Özgür (2007) Apoptotic blocks and chemotherapy resistance: unraveling Bcl-2 protein network. (Submitted)

Gül, Özgür and Calay, Ediz Süha and Sezerman, Uğur and Başağa, Hüveyda and Gürbüz, Yaşar (2007) Sandwich-type, antibody microarrays for the detection and quantification of cardiovascular risk markers. Sensors and actuators. B, Chemical, 125 (2). pp. 581-588. ISSN 0925-4005

Gül, Özgür and Calay, Ediz Süha and Başağa, Hüveyda and Gürbüz, Yaşar (2007) Sandwichtype, antibody microarrays for detection and quantification of cardiovascular risk markers. (Accepted/In Press)

Kütük, Özgür and Başağa, Hüveyda (2007) Apoptosis signalling by HNE: a role For JNK-c-Jun/AP-1 pathway. Redox Report, 12 (1-2). pp. 30-34. ISSN 13510002

Telci, Dilek and Başağa, Hüveyda and griffin, martin (2007) Sydecan-4 and Syndecan-2 are essential for RGD-independent cell adhesion via a transglutaminase-fibronectin matrix. (Submitted)

Bodur, Çağrı and Yılmaz, Sinem and Kütük, Özgür and Başağa, Hüveyda (2007) HNE (4-hydroxynonenal ) induces apoptosis via mitochondrial pathway with the involvement of Bcl-2 family members. In: 15th Euroconference on Apoptosis, Portorož, Slovenia

2006

Arslan, Mehmet Alper and Kütük, Özgür and Başağa, Hüveyda (2006) Protein kinases as drug targets in cancer. Current Cancer Drug Targets, 6 (7). pp. 623-634. ISSN 1568-0096

Kütük , Özgür and Başağa, Hüveyda (2006) Bcl-2 protein family: Implications in vascular apoptosis and atherosclerosis. Apoptosis, 11 (10). pp. 1661-1675. ISSN 1360-8185 (Print) 1573-675X (Online)

Gül, Özgür and Heves, Emre and Kaynak, Mehmet and Başağa, Hüveyda and Gürbüz, Yaşar (2006) Label-free, capacitive immunosensor for protein detection. In: IEEE SENSORS 2006 Conference, Daegu, South Korea

2005

Başağa, Hüveyda and Kütük, Özgür (2005) Resveratrol protects against 4hne induced apoptosis by blocking jnk and c jun/ap1 signaling. (Accepted/In Press)

Kütük, Özgür and Pedrech, A. and Harris, P. and Başağa, Hüveyda (2005) Pramanicin induces apoptosis in Jurkat leukemia cells; a role for JNK, p38 and caspase activation. Apoptosis, 10 (3). pp. 597-609. ISSN 1360-8185

Arslan, Mehmet Alper and Başağa, Hüveyda and Göktuna, Serkan İsmail (2005) Signaling pathways as drug targets in cancer. Advances in Molecular Medicine, supplement , 1 (2). pp. 69-74.

2004

Kütük, Özgür and Adli, Mazhar and Poli, Giuseppe and Başağa, Hüveyda (2004) Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts. Biofactors, 20 (1). pp. 1-10. ISSN 0951-6433

Kütük, Özgür and Başağa, Hüveyda (2004) Aspirin inhibits TNF alpha- and IL-1-induced NF-kappa B activation and sensitizes HeLa cells to apoptosis. Cytokine, 25 (5). pp. 229-237. ISSN 1043-4666

2003

Kütük, Özgür and Başağa, Hüveyda (2003) Aspirin prevents apoptosis and NF-kappa B activation induced by H2O2 in HeLa cells. Free Radical Research, 37 (12). pp. 1267-1276. ISSN 1071-5762

Kütük, Özgür and Başağa, Hüveyda (2003) Inflammation meets oxidation: NF-kappa B as a mediator of initial lesion development in atherosclerosis. Trends in molecular medicine, 9 (12). pp. 549-557. ISSN 1471-4914

1999

Onat, D. and Boscoboinik, D. and Azzi, A. and Başağa, Hüveyda (1999) Effect of alpha-tocopherol and silibin dihemisuccinate on the proliferation of human skin fibroblasts. Biotechnology and Applied Biochemistry, 29 (part 3). pp. 213-215. ISSN 0885-4513 (Print) 1470-8744 (Electronic)