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One-dimensional surface-imprinted polymeric nanotubes for specific biorecognition by initiated chemical vapor deposition (iCVD)

Özaydın İnce, Gözde and Armağan, Efe and Erdoğan, Hakan and Büyükserin, Fatih and Uzun, Lokman and Demirel, Gökhan (2013) One-dimensional surface-imprinted polymeric nanotubes for specific biorecognition by initiated chemical vapor deposition (iCVD). ACS Applied Materials & Interfaces, 5 (14). pp. 6447-6452. ISSN 1944-8244 (Print) 1944-8252 (Online)

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Official URL: http://dx.doi.org/10.1021/am401769r

Abstract

Molecular imprinting is a powerful, generic, and cost-effective technique; however, challenges still remain related to the fabrication and development of these systems involving nonhomogeneous binding sites, insufficient template removing, incompatibility with aqueous media, low rebinding capacity, and slow mass transfer. The vapor-phase deposition of polymers is a unique technique because of the conformal nature of coating and offers new possibilities in a number of applications including sensors, microfluidics, coating, and bioaffinity platforms. Herein, we demonstrated a simple but versatile concept to generate one-dimensional surface-imprinted polymeric nanotubes within anodic aluminum oxide (AAO) membranes based on initiated chemical vapor deposition (iCVD) technique for biorecognition of immunoglobulin G (IgG). It is reported that the fabricated surface-imprinted nanotubes showed high binding capacity and significant specific recognition ability toward target molecules compared with the nonimprinted forms. Given its simplicity and universality, the iCVD method can offer new possibilities in the field of molecular imprinting.

Item Type:Article
Uncontrolled Keywords:molecular imprinting; anodic aluminum oxide (AAO); initiated chemical vapor deposition (iCVD); biorecognition; polymeric nanotube; immunoglobulin G (IgG)
Subjects:Q Science > QD Chemistry > QD241-441 Organic chemistry
T Technology > TP Chemical technology > TP1080 Polymers and polymer manufacture
ID Code:26984
Deposited By:Gözde Özaydın İnce
Deposited On:25 Aug 2015 11:54
Last Modified:25 Aug 2015 11:54

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