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A watershed and active contours based method for dendritic spine segmentation in 2-photon microscopy images (2-Foton mikroskopi görüntülerindeki dendritik dikenlerin bölütlenmesi için watershed ve etkin çevritlere dayalı bir yöntem)

Erdil, Ertunç and Argunşah, Ali Özgür and Ünay, Devrim and Çetin, Müjdat (2013) A watershed and active contours based method for dendritic spine segmentation in 2-photon microscopy images (2-Foton mikroskopi görüntülerindeki dendritik dikenlerin bölütlenmesi için watershed ve etkin çevritlere dayalı bir yöntem). In: 21st Signal Processing and Communications Applications Conference (SIU 2013), Haspolat, Cyprus

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Official URL: http://dx.doi.org/10.1109/SIU.2013.6531263

Abstract

Analysing morphological and volumetric properties of dendritic spines from 2-photon microscopy images has been of interest to neuroscientists in recent years. Developing robust and reliable tools for automatic analysis depends on the segmentation quality. In this paper, we propose a new segmentation algorithm for dendritic spine segmentation based on watershed and active contour methods. First, our proposed method coarsely segments the dendritic spine area using the watershed algorithm. Then, these results are further refined using a region-based active contour approach. We compare our results and the results of existing methods in the literature to manual delineations of a domain expert. Experimental results demonstrate that our proposed method produces more accurate results than the existing algorithms proposed for dendritic spine segmentation.

Item Type:Papers in Conference Proceedings
Uncontrolled Keywords:Dendritic spine segmentation, Neural image analysis, Active contours
Subjects:T Technology > TK Electrical engineering. Electronics Nuclear engineering
ID Code:23474
Deposited By:Müjdat Çetin
Deposited On:13 Jan 2014 15:55
Last Modified:28 Feb 2014 10:36

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