A novel single-chip RF-voltage-controlled oscillator for bio-sensing applicationsHeves, Emre and Ergintav, Arzu and Kallempudi, S. Saravan and Gürbüz, Yaşar (2009) A novel single-chip RF-voltage-controlled oscillator for bio-sensing applications. In: 23rd Eurosensors Conference, Lausanne, Switzerland
Official URL: http://dx.doi.org/10.1016/j.proche.2009.07.251 AbstractA novel interdigiated capacitance (IDC) based affinity biosensor system is presented that detects C-Reactive Protein (CRP), a risk marker for cardiovascular diseases, and transmit the information to a distance location wirelessly. The biosensor system consist of a voltage controlled oscillator (VCO) and an IDC. In the presence of CRP the capacitance of the IDC changes and this directly reflects to the oscillation frequency of the VCO. In the presence of 800 ng/ml antigen the frequency of the system shifts from 1.9438 GHz to 1.94175 GHz and with 64 ug/ml frequency shifts from 1.95975 GHz to 1.94875 GHz with -120 dBc/Hz phase noise.
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