Label-free, capacitive immunosensor for protein detection

Abstract

This paper presents a biosensor implementation for the detection of protein molecules using specific antibodies. Affinity sensors allow the detection and quantification of target molecules in complex mixtures by affinity-based interactions. Immobilized antibody molecules are the probes that bind to specific protein molecules (targets) in biological fluids. In this study, interdigitated electrodes in the form of capacitance on glass slide were designed/simulated and used to measure the changes in the dielectric properties of the interdigated capacitances.